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Zharp1-211

Zharp1-211 is a potent and selective RIPK3 inhibitor. It suppresses JAK/STAT1-driven chemokine and MHC class II expression in intestinal epithelial cells, demonstrating efficacy in models of gastrointestinal inflammation and graft-versus-host disease (GVHD) by restoring intestinal homeostasis.

Product Specifications

CAS Number

2258671-41-7

Product Name Alternative

Zharp1211

Field of Research

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Purity

99.71% (May vary between batches)

Solubility

DMSO:8 mg/mL (17.88 mM)

Smiles

O=C (OC1CCOCC1) N2C=3C=C (C=NC3CC2) C=4C=CC5=NC (=CN5C4) NC (=O) C6CC6

Molecular Formula

C24H25N5O4

Molecular Weight

447.49

Storage Conditions

-20°C

Notes

For research use only.

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