Zharp1-211
Zharp1-211 is a potent and selective RIPK3 inhibitor. It suppresses JAK/STAT1-driven chemokine and MHC class II expression in intestinal epithelial cells, demonstrating efficacy in models of gastrointestinal inflammation and graft-versus-host disease (GVHD) by restoring intestinal homeostasis.
Product Specifications
CAS Number
2258671-41-7
Product Name Alternative
Zharp1211
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.71% (May vary between batches)
Solubility
DMSO:8 mg/mL (17.88 mM)
Smiles
O=C (OC1CCOCC1) N2C=3C=C (C=NC3CC2) C=4C=CC5=NC (=CN5C4) NC (=O) C6CC6
Molecular Formula
C24H25N5O4
Molecular Weight
447.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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