DBCO-PEG3 acetic-EVCit-PAB
This DBCO-PEG3-based ADC linker enables bioorthogonal conjugation via SPAAC click chemistry with azide-functionalized antibodies. It incorporates a cleavable valine-citrulline dipeptide and a self-immolative PAB spacer for targeted drug release, facilitating the construction of ADCs for both in vitro and in vivo cancer research applications.
Product Specifications
CAS Number
2253947-17-8
Field of Research
Cell Biology
Smiles
C (CCC (NCCOCCOCCOCC (N[C@H] (C (N[C@H] (C (N[C@H] (C (NC1=CC=C (CO) C=C1) =O) CCCNC (N) =O) =O) C (C) C) =O) CCC (OC (C) (C) C) =O) =O) =O) (=O) N2C=3C (C#CC=4C (C2) =CC=CC4) =CC=CC3
Molecular Formula
C54H72N8O13
Molecular Weight
1041.2
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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