NHS-Ala-Ala-Asn-active metabolite
This product is an NHS-activated tripeptide linker (Ala-Ala-Asn) designed for constructing cleavable antibody-drug conjugates (ADCs) . It enables the targeted delivery of KSP inhibitor payloads, facilitating research into ADC efficacy and mechanism in both in vitro cellular assays and in vivo preclinical cancer models.
Product Specifications
CAS Number
2231135-69-4
Field of Research
Signal Transduction
Smiles
[C@@H] (N (CC[C@H] (NC ([C@@H] (NC ([C@@H] (N (C ([C@@H] (NC (CCCC (ON1C (=O) CCC1=O) =O) =O) C) =O) C) C) =O) CC (N) =O) =O) C (NCCC (N[C@H] (CCC (O) =O) C (O) =O) =O) =O) C (CO) =O) (C (C) (C) C) C=2N (CC3=CC=CC=C3) C=C (C2) C4=C (F) C=CC (F) =C4
Molecular Formula
C56H72F2N10O17
Molecular Weight
1195.22
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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