P5 (PEG24) -VC-PAB-exatecan
This camptothecin-based linker-payload platform incorporates the potent exatecan derivative. It is designed for constructing antibody-drug conjugates (ADCs) and is utilized in oncology research for evaluating antitumor efficacy in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2928571-43-9
Field of Research
Pharmacology & Drug Discovery
Smiles
N (C (OCC1=CC=C (NC ([C@@H] (NC ([C@@H] (NC (=O) C2=CC=C (NP (OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO) (C#C) =O) C=C2) C (C) C) =O) CCCNC (N) =O) =O) C=C1) =O) [C@@H]3C4=C5C (C=6N (C5) C (=O) C7=C (C6) [C@] (CC) (O) C (=O) OC7) =NC=8C4=C (CC3) C (C) =C (F) C8
Molecular Formula
C100H151FN9O36P
Molecular Weight
2105.31
Storage Conditions
-20°C
Notes
For research use only.
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