MC-Gly-Gly-Phe-Gly-GABA-Exatecan
MC-Gly-Gly-Phe-Gly-GABA-Exatecan is a bifunctional agent combining an ADC linker with the topoisomerase I inhibitor Exatecan. It demonstrates cytotoxic and antitumor activity in both in vitro and in vivo models, with an IC50 of 22 μM, and is designed for targeted antibody conjugation in cancer research.
Product Specifications
CAS Number
1599439-52-7
Field of Research
Molecular Biology, Neuroscience; Pharmacology & Drug Discovery
Smiles
N (C (CCCNC (CNC ([C@H] (CC1=CC=CC=C1) NC (CNC (CNC (CCCCCN2C (=O) C=CC2=O) =O) =O) =O) =O) =O) =O) [C@@H]3C4=C5C (C=6N (C5) C (=O) C7=C (C6) [C@] (CC) (O) C (=O) OC7) =NC=8C4=C (CC3) C (C) =C (F) C8
Molecular Formula
C53H58FN9O12
Molecular Weight
1032.08
Storage Conditions
-20°C
Notes
For research use only.
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