NHS-Modified MMAF
This small molecule intermediate, referenced in patent WO2012143499A2, is specifically designed for synthesizing antibody-drug conjugates (ADCs) targeting mesothelin. It serves as a key cytotoxic payload linker component, enabling the development of targeted cancer therapeutics for preclinical in vitro and in vivo research.
Product Specifications
CAS Number
1404073-10-4
Smiles
C ([C@@H] (C (=O) N1CCCCO1) NC ([C@@H] ([C@@H] (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC ([C@@H] (N (CCCCCC (ON3C (=O) CCC3=O) =O) C) [C@@H] (C) C) =O) C (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]) C) =O) C=4C=5C (NC4) =CC=CC5
Molecular Formula
C55H86N8O12
Molecular Weight
1051.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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