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G3-VC-PAB-DMEA-Duocarmycin DM

Compound LD-1 (G3-VC-PAB-DMEA-Duocarmycin DM) is a duocarmycin-based linker-payload designed for constructing antibody-drug conjugates (ADCs) . It enables targeted drug delivery, with its cleavable linker facilitating the release of the potent cytotoxin in cancer cells, as studied in preclinical in vitro and in vivo models for oncology research.

Product Specifications

CAS Number

2415664-00-3

Smiles

C (Cl) [C@H]1C2=C (N (C (=O) C=3NC=4C (C3) =CC (OCCN (C) C) =CC4) C1) C=C (OC (N (CCN (C (OCC5=CC=C (NC ([C@@H] (NC ([C@@H] (NC (CNC (CNC (CN) =O) =O) =O) C (C) C) =O) CCCNC (N) =O) =O) C=C5) =O) C) C) =O) C=6C2=CC=CC6

Molecular Formula

C56H72ClN13O12

Molecular Weight

1154.7

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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