Val-Cit-PAB-DEA-Dxd
Val-Cit-PAB-DEA-Dxd (compound 81) is a cleavable drug-linker conjugate designed for constructing antibody-drug conjugates (ADCs) . It incorporates the topoisomerase I inhibitor Dxd, enabling targeted cytotoxicity. This reagent is widely used in ADC research and development for both in vitro and in vivo preclinical studies.
Product Specifications
CAS Number
2964543-53-9
Field of Research
Signal Transduction
Smiles
N (C (COC (N (CCN (C (OCC1=CC=C (NC ([C@@H] (NC ([C@H] (C (C) C) N) =O) CCCNC (N) =O) =O) C=C1) =O) C) C) =O) =O) [C@@H]2C3=C4C (C=5N (C4) C (=O) C6=C (C5) [C@] (CC) (O) C (=O) OC6) =NC=7C3=C (CC2) C (C) =C (F) C7
Molecular Formula
C50H61FN10O12
Molecular Weight
1013.08
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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