Val-Cit-PABC-Ahx-May
Val-Cit-PABC-Ahx-May is a cleavable linker-payload used in the synthesis of antibody-drug conjugates (ADCs) . It enables targeted drug delivery and intracellular release of the cytotoxic agent maytansine, facilitating research into ADC efficacy and mechanisms in both in vitro and in vivo cancer models.
Product Specifications
CAS Number
2126749-74-2
Field of Research
Signal Transduction
Smiles
C[C@]12[C@@] (O1) ([C@H] (C) [C@@]3 (C[C@] (O) ([C@H] (OC) /C=C/C=C (\C) /CC4=CC (N (C) C (=O) C[C@@H]2OC ([C@@H] (N (C (CCCCCNC (OCC5=CC=C (NC ([C@@H] (NC ([C@H] (C (C) C) N) =O) CCCNC (N) =O) =O) C=C5) =O) =O) C) C) =O) =C (Cl) C (OC) =C4) NC (=O) O3) [H]) [H]
Molecular Formula
C57H82ClN9O15
Molecular Weight
1168.77
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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