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MC-Val-D-Cit-PAB-PNP

MC-Val-D-Cit-PAB-PNP is a cleavable peptide linker for constructing antibody-drug conjugates (ADCs) . Its maleimidocaproyl group attaches to antibodies, while the p-nitrophenol ester enables efficient coupling to cytotoxic payloads. This linker is utilized in ADC research for targeted cancer therapy development in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

1350456-66-4

Field of Research

Signal Transduction

Smiles

[C@@H] (C (NC1=CC=C (COC (OC2=CC=C (N (=O) =O) C=C2) =O) C=C1) =O) (NC ([C@@H] (NC (CCCCCN3C (=O) C=CC3=O) =O) C (C) C) =O) CCCNC (N) =O

Molecular Formula

C35H43N7O11

Molecular Weight

737.76

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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