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NVS-STG2

NVS-STG2 is a small molecule STING agonist that functions as molecular glue, promoting oligomerization of human STING by binding between transmembrane domains of adjacent dimers. It potently activates STING-mediated immune responses in vitro and demonstrates antitumor efficacy in hSTING knock-in mouse models.

Product Specifications

CAS Number

3030588-01-0

Field of Research

Immunology & Inflammation

Purity

>98%

Form

Powder

Solubility

Soluble in DMSO (up to 40 mg/ml)

Smiles

O=C (O) C1=CC=C (NCC2=CC=C (C=C2) C3 (OCC (C) (C) CO3) C (C) (C) C) C (OC) =C1

Molecular Formula

C25H33NO5

Molecular Weight

427.5

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

4- ((4- (2- (tert-Butyl) -5,5-dimethyl-1,3-dioxan-2-yl) benzyl) amino) -3-methoxybenzoic acid

Available Sizes

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