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UNC 8732

UNC 8732 is a highly effective small molecule degrader of the NSD2 protein, achieving half-maximal degradation at 60 nM. This compound is a valuable chemical probe for investigating NSD2 biology in both cellular and in vivo models of cancer and other epigenetic-driven diseases.

Product Specifications

CAS Number

2929304-06-1

Field of Research

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Smiles

O=C (O) C (F) (F) F.O=C (NC1=CC=C2C (=C1) CCN (C (=O) CCCCCN) C2) C3=CC=C (C=C3) CN (C (=O) C4=CC=C5NC (=O) COC5=C4) C6CC6

Molecular Formula

C35H39N5O5.CF3CO2H

Molecular Weight

723.75

Storage Conditions

-20°C

Notes

For research use only.

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