(S) -BI 2536
(S) -BI 2536 is the less active enantiomer of the dual PLK1/BRD4 inhibitor BI 2536, exhibiting Ki values of 0.42 nM and 54 nM, respectively. This compound is a valuable chemical tool for probing kinase and bromodomain biology in cancer research, utilized in both in vitro biochemical assays and cellular studies.
Product Specifications
CAS Number
1241725-90-5
Smiles
C (C) [C@@H]1N (C=2C (N (C) C1=O) =CN=C (NC3=C (OC) C=C (C (NC4CCN (C) CC4) =O) C=C3) N2) C5CCCC5
Molecular Formula
C28H39N7O3
Molecular Weight
521.65
Storage Conditions
-20°C
Notes
For research use only.
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