MJ04
MJ04 is a potent and selective JAK3 inhibitor (IC50=2.03 nM) that impedes T cell differentiation and reduces LPS-induced cytokine production in macrophages. Demonstrating favorable pharmacokinetics, it has shown efficacy in promoting hair growth in a murine alopecia model with a high safety profile (LD50>2 g/kg) .
Product Specifications
CAS Number
2099014-23-8
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
FC=1C=CC (=CC1) C2=CN=C3NC=C (C=4N=C (N=CC4) NC5CC5) C3=C2
Molecular Formula
C20H16FN5
Molecular Weight
345.37
Storage Conditions
-20°C
Notes
For research use only.
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