MJ04
MJ04 is a potent and selective JAK3 inhibitor (IC50=2.03 nM) that impedes T cell differentiation and reduces LPS-induced cytokine production in macrophages. Demonstrating favorable pharmacokinetics, it has shown efficacy in promoting hair growth in a murine alopecia model with a high safety profile (LD50>2 g/kg) .
Product Specifications
CAS Number
2099014-23-8
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
FC=1C=CC (=CC1) C2=CN=C3NC=C (C=4N=C (N=CC4) NC5CC5) C3=C2
Molecular Formula
C20H16FN5
Molecular Weight
345.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
250323-AP 100 µL
POU5F2 (POU Domain Class 5, Transcription Factor 2, DKFZp686P02123, FLJ25680, SPRM-1) (AP) discontinued
Sign In for Pricing
View Details 
bs-9511R-BF750 100 µL
PAR4 Polyclonal Antibody, AbBy Fluor™ 750 Conjugated
Sign In for Pricing
View Details