PLK1-IN-9
PLK1-IN-9 (Compound M2) is a potent PLK1 inhibitor with IC50 values in the sub-micromolar range against key phosphopeptide substrates. It demonstrates robust anti-proliferative and pro-apoptotic activity in various cancer cell lines (e.g., HeLa, HepG2) and has shown efficacy in suppressing tumor growth in a HepG2 xenograft model, supporting its use in oncology research.
Product Specifications
CAS Number
893772-67-3
Field of Research
Cell Biology, Signal Transduction
Smiles
O=C1N=C2C (=NC=3C=C (C=CC3N2C) C (F) (F) F) C (=O) N1
Molecular Formula
C12H7F3N4O2
Molecular Weight
296.20
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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