PLK1-IN-9

PLK1-IN-9 (Compound M2) is a potent PLK1 inhibitor with IC50 values in the sub-micromolar range against key phosphopeptide substrates. It demonstrates robust anti-proliferative and pro-apoptotic activity in various cancer cell lines (e.g., HeLa, HepG2) and has shown efficacy in suppressing tumor growth in a HepG2 xenograft model, supporting its use in oncology research.