GNE7599
GNE7599 is a potent, orally bioavailable von Hippel-Lindau (VHL) ligand (Kd = 540 pM) designed for PROTAC development. It serves as a key component for constructing bifunctional degraders to study targeted protein degradation in both cellular and in vivo research models.
Product Specifications
CAS Number
2771069-76-0
Field of Research
Pharmacology & Drug Discovery
Smiles
[C@@H] (C (=O) N1[C@H] (C (N[C@@H]2C=3C (=CC (=CC3) C4=C (C) N=CS4) CCCC2) =O) C[C@@H] (O) C1) ([C@] (C) (C) C) N5C=C (N=N5) C6CC6
Molecular Formula
C31H40N6O3S
Molecular Weight
576.75
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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