ASK1-IN-6
ASK1-IN-6 (Compound 32) is a potent and selective ASK1 inhibitor (IC50 = 25 nM) with demonstrated blood-brain barrier penetration (Kp, uu = 0.46) . It shows anti-inflammatory properties and has been shown to ameliorate pathology in the Tg4510 Alzheimer's disease mouse model, supporting its use in neuroscience and inflammation research.
Product Specifications
CAS Number
2407451-82-3
Field of Research
Cell Biology, Signal Transduction
Smiles
[C@@H] (C (F) (F) F) (C) N1C (=NN=C1) C=2N=C (NC (=O) C3=C (OC) N=CC (F) =C3) C=CC2
Molecular Formula
C17H14F4N6O2
Molecular Weight
410.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
33055-05171 5x 30 µg
Human Tryptophanyl tRNA synthetase AssayLite™ Antibody (PerCP Conjugate)
Sign In for Pricing
View Details 
P3113-98J-ML490 100 µL
PBK, CT (PDZ Binding Kinase, Cancer/testis Antigen 84, CT84, Lymphokine-activated Killer T-cell-originated Protein Kinase, MAPKK-like Protein Kinase, Nori-3, Spermatogenesis-related Protein Kinase, SPK, T-LAK Cell-originated Protein Kinase, TOPK) (MaxLight 490) discontinued
Sign In for Pricing
View Details 374189-01 20 µg
MEOX1, Recombinant, Human, aa1-254, GST-Tag (Homeobox Protein MOX-1)
Sign In for Pricing
View Details 374189-02 100 µg
MEOX1, Recombinant, Human, aa1-254, GST-Tag (Homeobox Protein MOX-1)
Sign In for Pricing
View Details E45H01899-2 20 µg
NFATC4 (NM_001136022) Human Over-expression Lysate
Sign In for Pricing
View Details 
K2175602 1.0 µg DNA
SLC25A2 sgRNA CRISPR Lentivector (Human) (Target 1)
Sign In for Pricing
View Details