ASK1-IN-6
ASK1-IN-6 (Compound 32) is a potent and selective ASK1 inhibitor (IC50 = 25 nM) with demonstrated blood-brain barrier penetration (Kp, uu = 0.46) . It shows anti-inflammatory properties and has been shown to ameliorate pathology in the Tg4510 Alzheimer's disease mouse model, supporting its use in neuroscience and inflammation research.
Product Specifications
CAS Number
2407451-82-3
Field of Research
Cell Biology, Signal Transduction
Smiles
[C@@H] (C (F) (F) F) (C) N1C (=NN=C1) C=2N=C (NC (=O) C3=C (OC) N=CC (F) =C3) C=CC2
Molecular Formula
C17H14F4N6O2
Molecular Weight
410.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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