Zemprocitinib
Zemprocitinib (Compound 1) is a potent and selective JAK1 inhibitor, demonstrating IC50 values of 5.95 nM for JAK1, 141.3 nM for JAK2, and 119 nM for TYK2. This small molecule is a valuable research tool for investigating JAK-STAT signaling in both cellular assays and preclinical models of immune-mediated diseases.
Product Specifications
CAS Number
2417414-44-7
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
O=S (=O) (NC12CC (N3C=NC4=CNC5=NC=CC5=C43) (C1) C2) CCC
Molecular Formula
C16H19N5O2S
Molecular Weight
345.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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