PROTAC STING Degrader-2
PROTAC STING Degrader-2 is a covalent bifunctional degrader that targets the STING protein for ubiquitination and proteasomal degradation with a DC50 of 0.53 μM. It is a valuable chemical tool for investigating STING-dependent signaling in autoimmune disease models, both in cellular assays and in vivo studies.
Product Specifications
CAS Number
3023095-61-3
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
C ([C@@H] (NC (CCC (NCCCNC (=O) C1=CC (S (=O) (=O) N2C=C (C (NCCCCCC (OC3=C (NS (=O) (=O) C4=CC=C (F) C=C4) C=C (NC (=O) C5=CC=C (C=C5) C6=CC=CC=C6) C=C3) =O) =O) C=CC2=O) =CC=C1) =O) =O) [C@@] (C) (C) C) (=O) N7[C@H] (C (N[C@@H] (C) C8=CC=C (C=C8) C=9SC=NC9C) =O) C[C@@H] (O) C7
Molecular Formula
C74H79FN10O15S3
Molecular Weight
1463.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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