EGFR T790M/L858R-IN-8
EGFRT790M/L858R-IN-8 (compound 9) is a selective inhibitor of the EGFR T790M/L858R mutant with an IC50 of 56.8 μM. It serves as a valuable research tool for investigating resistant non-small cell lung cancer (NSCLC) in biochemical assays, though it exhibits limited antiproliferative activity in cell lines like A549 and NCI-H1975.
Product Specifications
CAS Number
333419-97-9
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O=C (NC=1C=CC=C (Br) C1) C=2C (=O) NC=3C=CC=CC3C2O
Molecular Formula
C16H11BrN2O3
Molecular Weight
359.17
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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