TEAD-IN-13
TEAD-IN-13 (64) is a potent, orally bioavailable TEAD autopalmitoylation inhibitor with an IC50 under 100 nM. Its 3.2-hour half-life in mice supports in vivo studies of Hippo pathway dysregulation in cancer research, enabling investigation of TEAD-dependent transcription in cellular and animal models.
Product Specifications
CAS Number
3034813-74-3
Field of Research
Stem Cell & Developmental Biology
Smiles
C (=O) (C1C (C1) C=2C=3C (C=C (OC4=CC=C (C (F) (F) F) C=C4) C2) =CN (C) N3) N5C[C@H] (O) [C@@H] (O) C5
Molecular Formula
C23H22F3N3O4
Molecular Weight
461.43
Storage Conditions
-20°C
Notes
For research use only.
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