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TEAD-IN-13

TEAD-IN-13 (64) is a potent, orally bioavailable TEAD autopalmitoylation inhibitor with an IC50 under 100 nM. Its 3.2-hour half-life in mice supports in vivo studies of Hippo pathway dysregulation in cancer research, enabling investigation of TEAD-dependent transcription in cellular and animal models.

Product Specifications

CAS Number

3034813-74-3

Field of Research

Stem Cell & Developmental Biology

Smiles

C (=O) (C1C (C1) C=2C=3C (C=C (OC4=CC=C (C (F) (F) F) C=C4) C2) =CN (C) N3) N5C[C@H] (O) [C@@H] (O) C5

Molecular Formula

C23H22F3N3O4

Molecular Weight

461.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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