Pan-RAS-IN-2
Pan-RAS-IN-2 (6A) is a molecular glue degrader that induces a ternary complex with cyclophilin A and active RAS, blocking RAF recruitment and downstream signaling. It potently inhibits the proliferation of RAS-mutant cancer cells in vitro, making it a valuable chemical probe for oncology research targeting the RAS pathway.
Product Specifications
CAS Number
3034673-92-9
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
99.81% (May vary between batches)
Smiles
O=C1OCC (C) (C) CC=2C3=CC (=CC=C3N (C2C=4C=C (C=NC4C (OC) C) N5CCN (C) CC5) CC) C=6N=C (SC6) CC (NC (=O) C7C (C) C7C) C (=O) N8NC1C9CC8C9
Molecular Formula
C46H60N8O5S
Molecular Weight
837.08
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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