Polθ-IN-3
Polθ-IN-3 (Compound 113) is an orally bioavailable, small-molecule inhibitor of DNA Polymerase Theta. It demonstrates antitumor efficacy in research models, making it a valuable tool for studying DNA repair pathways, synthetic lethality, and cancer biology in both cellular and animal studies.
Product Specifications
CAS Number
2922287-81-6
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology
Smiles
O=C (NC1=NN=C (C#CC2CC2) S1) C=3C=NC (=CC3C4=CC (=NC=C4OC) C (F) F) C5=NN (C=C5) C
Molecular Formula
C24H19F2N7O2S
Molecular Weight
507.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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