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Polθ-IN-3

Polθ-IN-3 (Compound 113) is an orally bioavailable, small-molecule inhibitor of DNA Polymerase Theta. It demonstrates antitumor efficacy in research models, making it a valuable tool for studying DNA repair pathways, synthetic lethality, and cancer biology in both cellular and animal studies.

Product Specifications

CAS Number

2922287-81-6

Field of Research

Cell Biology, Infectious Disease & Virology, Molecular Biology

Smiles

O=C (NC1=NN=C (C#CC2CC2) S1) C=3C=NC (=CC3C4=CC (=NC=C4OC) C (F) F) C5=NN (C=C5) C

Molecular Formula

C24H19F2N7O2S

Molecular Weight

507.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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