VNPP433-3β
VNPP433-3β is a molecular glue degrader targeting the androgen receptor (AR), its splice variants, and Mnk1/2. It potently inhibits prostate cancer cell proliferation in vitro and demonstrates in vivo efficacy by suppressing tumor growth in a CWR22Rv1 xenograft model.
Product Specifications
CAS Number
1630820-51-7
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
C[C@@]12[C@] ([C@]3 ([C@] (CC1) ([C@]4 (C) C (=CC3) C[C@H] (CC4) N5C=CN=C5) [H]) [H]) (CC=C2N6C=7C (N=C6) =CC=CC7) [H]
Molecular Formula
C29H34N4
Molecular Weight
438.61
Storage Conditions
-20°C
Notes
For research use only.
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