CBu-Cit-PROTAC BRD4 Degrader-5
CBu-Cit-PROTAC BRD4 Degrader-5 is a small molecule PROTAC that induces potent degradation of the BRD4 protein. It demonstrates efficacy in cellular models of breast cancer, independent of HER2 status, making it a useful chemical probe for oncology research and targeted protein degradation studies.
Product Specifications
CAS Number
2417369-73-2
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
CC=1C2=C (N3C ([C@H] (CC (NCCOCCOCCOCC (N[C@H] (C (=O) N4[C@H] (C (NCC5=CC=C (C=C5) C6=C (C) N=CS6) =O) C[C@@H] (OCNC (OCC7=CC=C (NC ([C@@H] (NC (=O) C8 (C (NCCCCCN9C (=O) C=CC9=O) =O) CCC8) CCCNC (N) =O) =O) C=C7) =O) C4) [C@@] (C) (C) C) =O) =O) N=C2C%10=CC=C (Cl) C=C%10) =NN=C3C) SC1C
Molecular Formula
C79H99ClN16O16S2
Molecular Weight
1628.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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