PROTAC IRAK4 degrader-10
PROTACIRAK4 degrader-10 is a potent, orally bioavailable PROTAC molecule that utilizes a Cereblon ligand to induce IRAK4 degradation. It achieves a DC50 of 7.68 nM and up to 95.94% degradation in HEK293 cells, making it a valuable tool for investigating IRAK4's role in immunology and oncology research.
Product Specifications
CAS Number
3033829-95-4
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C (NC1=CN2C=C (N=C2C (F) =C1C (O) (C) C) C3CCN (CC3) CC4CCN (C5=CC=C6C (=O) N (C (=O) C6=C5) C7C (=O) NC (=O) CC7) CC4) C=8N=C (C=CC8) C9CC9 (F) F
Molecular Formula
C43H45F3N8O6
Molecular Weight
826.86
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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