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AD16

AD16 (Acetamide) is a small molecule inhibitor of the LINE-1 retrotransposon endonuclease (IC50 = 4.7 μM) . It effectively reduces LINE-1 retrotransposition in cellular models, including senescent cells, thereby alleviating associated genomic instability and inflammatory responses in research applications.

Product Specifications

CAS Number

311315-04-5

Field of Research

Cell Biology

Smiles

O=C (NC1=CC=C2OC (=NC2=C1) C3=CC=C (C=C3) CC (=O) CSC4=NN=C5N4N=CN5N) CSC6=NN=C7N6N=CN7N

Molecular Formula

C24H20N14O3S2

Molecular Weight

616.64

Storage Conditions

-20°C

Notes

For research use only.

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