GGFG-PAB-Exatecan
GGFG-PAB-Exatecan is a drug-linker conjugate designed for ADC synthesis, combining the potent topoisomerase I inhibitor Exatecan with a cleavable GGFG-PAB linker. This construct is widely used in research for developing antibody-drug conjugates, enabling targeted cytotoxicity studies in both in vitro and in vivo cancer models.
Product Specifications
CAS Number
251459-32-2
Field of Research
Molecular Biology, Pharmacology & Drug Discovery
Smiles
N (C (OCC1=CC=C (NC (CNC ([C@H] (CC2=CC=CC=C2) NC (CNC (CN) =O) =O) =O) =O) C=C1) =O) [C@@H]3C4=C5C (C=6N (C5) C (=O) C7=C (C6) [C@] (CC) (O) C (=O) OC7) =NC=8C4=C (CC3) C (C) =C (F) C8
Molecular Formula
C47H47FN8O10
Molecular Weight
902.92
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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