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HOE 689

HOE 689 (Ramnodigin), a digitoxin analog, is a cytotoxic agent that induces apoptosis in NCI-H460 lung cancer cells with an IC50 of 52 nM. This small molecule is used in cancer research for in vitro studies exploring cardenolide mechanisms and potential anti-tumor applications.

Product Specifications

CAS Number

33156-28-4

Field of Research

Cell Biology

Smiles

O[C@@]12[C@]3 ([C@@] ([C@]4 (C) [C@] (CC3) (C[C@@H] (O[C@@H]5O[C@@H] (C) [C@H] (O) CC5) CC4) [H]) (CC[C@]1 (C) [C@H] (CC2) C=6COC (=O) C6) [H]) [H]

Molecular Formula

C29H44O6

Molecular Weight

488.66

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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