DNMT1-IN-3
DNMT1-IN-3 (7t-S) is a potent small molecule inhibitor of DNA methyltransferase 1 (DNMT1) with an IC50 of 0.777 μM. It promotes apoptosis and induces G0/G1 phase cell cycle arrest, making it a useful tool for epigenetic research in cancer biology, both in vitro and in vivo.
Product Specifications
CAS Number
3025012-68-1
Field of Research
Epigenetics & Chromatin
Smiles
C ([C@@H] (C (O) =O) N1C (=O) C=2C (C1=O) =CC=CC2) N3C=4C (C=5C3=CC=C (Cl) C5) =CC (Cl) =CC4Cl
Molecular Formula
C23H13Cl3N2O4
Molecular Weight
487.72
Storage Conditions
-20°C
Notes
For research use only.
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JMJD2D (Jumonji Domain Containing 2D, JMJD2D, KDM4D, Lysine-specific Demethylase 4D, JmjC Domain-containing Histone Demethylation Protein 3D, JHDM3D, FLJ10251, MGC141909)
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