IRE1a-IN-1
IRE1a-IN-1 (Compound 10) is a potent small molecule inhibitor of IRE1α, demonstrating an IC50 of <100 nM against XBP1 mRNA splicing. It is widely used in cancer research to study endoplasmic reticulum stress pathways in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
3033375-01-5
Field of Research
Cell Biology
Smiles
O=CC=1C (O) =C2OCCCC2=C3C1OC (=O) C (=C3C) CC (=O) N4CCC (F) (F) C4
Molecular Formula
C20H19F2NO6
Molecular Weight
407.36
Storage Conditions
-20°C
Notes
For research use only.
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