XOR/URAT1-IN-1
XOR/URAT1-IN-1 is a potent dual inhibitor of xanthine oxidoreductase (IC50 = 6 nM) and the URAT1 transporter (IC50 = 12.9 μM) . It is a valuable research tool for studying urate metabolism and has demonstrated efficacy in lowering serum uric acid in a potassium oxonate/hypoxanthine-induced mouse model of hyperuricemia.
Product Specifications
CAS Number
2810137-86-9
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
O=C (O) C=1C=CC (=CC1O) C2=CN=CC (=C2) NC=3C=CC=C (Cl) C3
Molecular Formula
C18H13ClN2O3
Molecular Weight
340.76
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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