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KIF18A-IN-10

KIF18A-IN-10 (Compound 24) is a highly potent, nanomolar-range inhibitor of the mitotic kinesin KIF18A (IC50 = 3.8 nM) . It demonstrates robust in vitro anticancer activity, with IC50 values under 100 nM in cell lines such as OVCAR3 and MDA-MB-157, supporting its use in cancer biology and drug discovery research.

Product Specifications

CAS Number

3034542-28-1

Field of Research

Signal Transduction

Smiles

O=C (NC1=NC2=C (C=NN2C3CC (F) (F) C3) C=C1) C4=CC=C (C=C4N5CCC6 (CC5) CC6) NS (=O) (=O) CCO

Molecular Formula

C26H30F2N6O4S

Molecular Weight

560.62

Storage Conditions

-20°C

Notes

For research use only.

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