KIF18A-IN-10
KIF18A-IN-10 (Compound 24) is a highly potent, nanomolar-range inhibitor of the mitotic kinesin KIF18A (IC50 = 3.8 nM) . It demonstrates robust in vitro anticancer activity, with IC50 values under 100 nM in cell lines such as OVCAR3 and MDA-MB-157, supporting its use in cancer biology and drug discovery research.
Product Specifications
CAS Number
3034542-28-1
Field of Research
Signal Transduction
Smiles
O=C (NC1=NC2=C (C=NN2C3CC (F) (F) C3) C=C1) C4=CC=C (C=C4N5CCC6 (CC5) CC6) NS (=O) (=O) CCO
Molecular Formula
C26H30F2N6O4S
Molecular Weight
560.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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