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SN-398

SN-398 is a potent camptothecin-derived antitumor agent that acts as a topoisomerase I (Topo I) inhibitor, stabilizing the Topo I-DNA complex to induce lethal DNA breaks. It demonstrates enhanced antiproliferative activity in vitro, such as in HeLa cell assays, and is a valuable tool for studying Topo I-targeted cancer therapies.

Product Specifications

CAS Number

124623-00-3

Field of Research

Molecular Biology

Smiles

O=C1N2C (C=3C (C2) =C (CC) C=4C (N3) =CC (F) =C (O) C4) =CC5=C1COC (=O) [C@@]5 (CC) O

Molecular Formula

C22H19FN2O5

Molecular Weight

410.40

Storage Conditions

-20°C

Notes

For research use only.

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