TEAD-IN-12
TEAD-IN-12 (58B) is a potent, orally bioavailable small molecule inhibitor of the TEAD transcription factors, with sub-100 nM IC50 activity and a 3.6-hour half-life in mice. It is a valuable chemical probe for investigating the Hippo signaling pathway in cancer research, enabling both in vitro mechanistic studies and in vivo efficacy models.
Product Specifications
CAS Number
3034813-66-3
Field of Research
Stem Cell & Developmental Biology
Purity
99.05% (May vary between batches)
Smiles
C (=O) ([C@@H]1[C@H] (C1) C=2C=3C (C=C (OC4=CC=C (C (F) (F) F) C=C4) C2) =CN (C) N3) N5CC (O) C5
Molecular Formula
C22H20F3N3O3
Molecular Weight
431.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
VAng-Lsx02084-500gEcoli 500 µg (E. coli)
Recombinant Clostridium Thermocellum rpsJ Protein (aa 1-103)
Sign In for Pricing
View Details 
MBS2505013-01 24 Tests
Guinea pig MLCK/MYLK (Myosin Light Chain Kinase) ELISA Kit
Sign In for Pricing
View Details MBS2505013-02 48 Tests
Guinea pig MLCK/MYLK (Myosin Light Chain Kinase) ELISA Kit
Sign In for Pricing
View Details