TD114-2
TD114-2 (compound 29) is a potent, selective GSK-3β inhibitor (IC50 = 48 nM) with selectivity conferred by a key interaction with ARG141. It is a valuable research tool for studying GSK-3β's role in diabetes and neurodegenerative disease models, applicable in both in vitro and in vivo experimental settings.
Product Specifications
CAS Number
436866-52-3
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Smiles
O=C1NC (=O) C=2C3=CN (C=4C=CC=CC34) CCOCCOCCOCCOCCN5C=C (C=6C=CC=CC65) C12
Molecular Formula
C30H31N3O6
Molecular Weight
529.58
Storage Conditions
-20°C
Notes
For research use only.
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