Prexasertib lactate
Prexasertib lactate is a potent, ATP-competitive CHK1 inhibitor (Ki=0.9 nM) with additional activity against CHK2 and RSK1. It induces DNA damage and apoptosis, demonstrating antitumor efficacy in both cellular assays and in vivo xenograft models across various cancer research fields.
Product Specifications
CAS Number
2781996-46-9
Field of Research
Cell Biology, Molecular Biology
Smiles
[C@@H] (C (O) =O) (C) O.O (CCCN) C1=C (C (OC) =CC=C1) C2=CC (NC=3C=NC (C#N) =CN3) =NN2
Molecular Formula
C21H25N7O5
Molecular Weight
455.47
Storage Conditions
-20°C
Notes
For research use only.
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