Verticilide
Verticilide is a ryanodine receptor inhibitor that potently blocks ryanodine binding in insect (cockroach) receptors with an IC50 of 4.2 μM, while showing significantly weaker activity against mammalian (mouse) receptors (IC50 = 53.9 μM) . This selective profile makes it a useful research tool for studying insecticide targets and comparative pharmacology in both in vitro binding assays and potential insect toxicology studies.
Product Specifications
CAS Number
693778-57-3
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
C (CCCC) [C@@H]1C (=O) N (C) [C@@H] (C) C (=O) O[C@H] (CCCCC) C (=O) N (C) [C@@H] (C) C (=O) O[C@H] (CCCCC) C (=O) N (C) [C@@H] (C) C (=O) O[C@H] (CCCCC) C (=O) N (C) [C@@H] (C) C (=O) O1
Molecular Formula
C44H76N4O12
Molecular Weight
853.09
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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