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Verticilide

Verticilide is a ryanodine receptor inhibitor that potently blocks ryanodine binding in insect (cockroach) receptors with an IC50 of 4.2 μM, while showing significantly weaker activity against mammalian (mouse) receptors (IC50 = 53.9 μM) . This selective profile makes it a useful research tool for studying insecticide targets and comparative pharmacology in both in vitro binding assays and potential insect toxicology studies.

Product Specifications

CAS Number

693778-57-3

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Smiles

C (CCCC) [C@@H]1C (=O) N (C) [C@@H] (C) C (=O) O[C@H] (CCCCC) C (=O) N (C) [C@@H] (C) C (=O) O[C@H] (CCCCC) C (=O) N (C) [C@@H] (C) C (=O) O[C@H] (CCCCC) C (=O) N (C) [C@@H] (C) C (=O) O1

Molecular Formula

C44H76N4O12

Molecular Weight

853.09

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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