TYA-018
TYA-018 is a selective, orally bioavailable HDAC6 inhibitor developed for cardiovascular research. It exhibits cardioprotective effects by mitigating sarcomere damage and reducing Nppb expression, making it a valuable tool for in vivo and in vitro studies of dilated cardiomyopathy and heart failure mechanisms.
Product Specifications
CAS Number
2653254-31-8
Product Name Alternative
HDAC6, TYA 018, TYA018
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Purity
98.64% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.59 mM) ; DMSO:80 mg/mL (183.96 mM)
Smiles
O=S (=O) (N (C=1C=CC=C (Cl) C1) CC2=NC=C (S2) C3=NN=C (O3) C (F) F) CC
Molecular Formula
C15H13ClF2N4O3S2
Molecular Weight
434.87
Storage Conditions
-20°C
Notes
For research use only.
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