ARV-393 HCl
ARV-393 HCl is a potent, orally bioavailable PROTAC degrader targeting the BCL6 oncoprotein. It demonstrates robust antitumor activity in both in vitro and in vivo models, making it a valuable chemical probe for researching B-cell non-Hodgkin's lymphomas.
Product Specifications
Product Name Alternative
ARV-393 HCl (2851885-95-3 Free base), ARV393HCl (2851885953Freebase), BCL, PROTAC
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
99.35% (May vary between batches)
Smiles
Cl.CNC (=O) COc1cc2cc (Nc3nc (ncc3Cl) N3CCC (CC3) O[C@H]3C[C@@H] (C3) N3CCC (CC3) c3ccc4C (=O) N (Cc4c3F) C3CCC (=O) NC3=O) ccc2n (C (C) C) c1=O
Molecular Formula
C46H54Cl2FN9O7
Molecular Weight
934.88
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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