G-1749
G-1749 is a research compound that modulates IRE1 activity. It stimulates the RNase function of unphosphorylated IRE1 and the IRE1-KR-0P mutant while inhibiting the phosphorylated form (IRE1-3P), without affecting the IRE1 monomer-dimer equilibrium. This makes it a valuable tool for studying the unfolded protein response (UPR) in both cellular and biochemical assays.
Product Specifications
CAS Number
2245057-57-0
Product Name Alternative
G 1749, G1749
Purity
96.22% (May vary between batches)
Smiles
CCOC (=O) Nc1cccc2c (Oc3ncccc3-c3ccnc (N[C@H]4CCCNC4) n3) c (C) ccc12
Molecular Formula
C28H30N6O3
Molecular Weight
498.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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