BI-4732
BI-4732 is a brain-penetrant EGFR tyrosine kinase inhibitor effective against T790M mutations. It is used in preclinical research for studying EGFR-driven cancers, demonstrating antitumor activity in both in vitro assays and in vivo models of non-small cell lung cancer and brain metastases.
Product Specifications
CAS Number
2769715-68-4
Product Name Alternative
BI4732, EGFR
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.88% (May vary between batches)
Solubility
DMSO:4 mg/mL (6.75 mM)
Smiles
CN1C=2C (=C (N=C (C2) N3C=4C (C=N3) =C (C) N=C (C4) C=5C (OC) =CC=NC5) N6[C@@]7 (C[C@] (C6) (OC7) [H]) [H]) N=C1N8C[C@@]9 (N (CC8) CCC9) [H]
Molecular Formula
C32H36N10O2
Molecular Weight
592.69
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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