(R, S, S) -VH032
(R, R, S) -VH032 is a VHL E3 ligase ligand used to construct PROTAC degraders, such as the tau-targeting molecule C004019. It disrupts the VHL/HIF-1α interaction and has been employed in both cellular and in vivo studies to develop targeted protein degradation therapies for neurodegenerative and oncological research.
Product Specifications
CAS Number
2230826-33-0
Field of Research
Pharmacology & Drug Discovery
Smiles
C (NCC1=CC=C (C=C1) C=2SC=NC2C) (=O) [C@@H]3N (C ([C@H] (C (C) (C) C) N) =O) C[C@@H] (O) C3
Molecular Formula
C22H30N4O3S
Molecular Weight
430.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
51214141 1x 10^6 Cells / 1.0 mL
ZFPL1 CRISPR Knock Out 293T Cell Line (Human)
Sign In for Pricing
View Details 
BNC741579-100 1x 100 µL
SREBP2 (SREBP2/1579), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details